A Race toward Vaccine for COVID-19

A Race Toward The Vaccine For COVID-19

 

Corona virus belongs to the family of coronaviridae. The first case of corona virus was reported from Wuhan china in December 2019. In 2002 SARS and in 2012 MERS were also occurred of coronaviridae family but this time the virus is novel with aspect to its glycoprotein structure. Therefore there is no available treatment for it.

The corona virus when get entry to the body it attach with the angiotensin converting enzyme 2 receptor  but the mode of action of corona virus is still unknown which restricts the development of vaccine. Recently China released the fully sequenced genome of corona virus to help the scientist in vaccine development throughout the globe.

 

Vaccines are become big market for drug companies. Vaccine is become a 35 billion dollar market. Creating vaccines for emergency pandemics becomes tricky unfortunately creating vaccines and medicines against these emergency pandemics is not good business over history. Companies have not been necessarily rewarded for treatment and vaccine against an emergency outbreak. We have seen it in ZEKA and SARS. This is not a good business to the investors in drug companies because it requires more than a 100 million dollars and give profit for a short period of time to address the problem so it’s not a big money maker for drug companies. Beside the limitation many companies and organization are working for the vaccine of corona virus such as BARDA. BARDA working to develop an emergency vaccine for COVID-19. BARDA also announce a partnership with SANOFI and Johnson & Johnson for the development of rDNA vaccine. Bill gates foundation and the governments of Germany, japan and Norway also participating in the vaccine development. Biotech Moderna Company trying to develop a vaccine for corona virus through new mRNA technique.

Currently this company leads the race of coronavirus vaccine. Moderna plans to start a small scale human trail of corona virus vaccine in Seattle Washington. A healthy volunteer in Seattle is the first person in the U.S. to receive a dose of an experimental coronavirus vaccine as part of a new clinical trial, government health officials announced on (March 16). But according to the Director, National Institute of Allergy and Infectious diseases Dr. Anthony Fauci “it will take 3 months or more to say it is safe and if it show that it is safe then phase 2 trial will be started to show that it works”. Johnson & Johnson are also in the race by working on vaccine for deadly corona virus. They using the deactivated version of corona virus. Inovio pharmaceuticals working with the Chinese companies to speed up the development of its DNA vaccine, Issued an initial grant of 9 million dollars to the company. The vaccine are here in phase 1 trails but it will take years to be available to the public. Many other companies are also working on different treatments other than vaccine. Gilead (Remdesivir) is an antiviral drug in the class of nucleotide analogs has been tested in china and found effective against coronavirus, now expanding to other countries to treat the corona virus patient. Development of vaccine is not an easy task it takes years but hoped so to develop it soon by scientist. ALLAH protects everyone from COVID-19 in the entire globe and recover the infected ones Ameen.

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